Since its introduction, fluorescein angiography has been widely used in diagnosing and evaluating treatment of diseases of the retina, uveal tract, and optic nerve.
A case with Behcet´s disease was studied by means of fluorescein fundus angiography. This, presummed a retinal angiopathy, has been diagnosed Behcet´s disease after developing symptoms of hypopyon iritis, intermittent fever, aphthous stomatitis, and genital ulceration.
The fluorescein angiography in Behcet´s disease is typically shown a specific finding. Extravasation of the dye was most conspicuous in capillaries over-lying the optic nerve head, the radial peripapillary capillaries, retinal capillaries proper and retinal veins. Retinal arteriols generally lacked extravasation phenomenon. Edematous swelling of the disc, diffuse turbidity of the posterior fundus and macular cysts are regarded as cogsquences of the fluorographically confirmed increased permeability of the retinal vessels with resultant edema of the neuropithelium.
Pathogenesis of the retinal angiopathy in Behcet´s disease and diseases with retinal edema and hyperpermeability were discussed with references.
The fluorographic findings thus indicate that the pathological involvement of retinal vessels play a major factor in the diagnosis and prognosis of ocular manifestation of Behcet´s disease.
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